The RABBIT ANTI HUMAN CD281 (N-TERMINAL) Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to CD281, TIL, TLR1, and toll like receptor 1. This antibody recognizes Human, and Mouse antigen. The RABBIT ANTI HUMAN CD281 (N-TERMINAL) Antibody has been validated for the following applications: Immunohistochemistry, and Western Blot.
Description
Rabbit anti Human CD281 antibody detects an epitope within the N-terminal (NT) region of CD281, also known as toll like receptor 1 (TLR1). TLRs recognize pathogen associated molecular patterns (PAMPs) that are expressed on infectious agents, and serve as an important link between the innate and adaptive immune response through the production of cytokines. TLR1 is co-expressed with TLR2 on monocytes and dendritic cells where they form heterodimers that can recognize peptidoglycan and bacterial lipopeptides, and in particular triacylated lipoproteins. TLR1 can also regulate other TLR responses; TLR1 can associate with TLR4 and inhibit its signalling in endothelial cells, and can associate with TLR2 to inhibit the TLR2/TLR6 mediated response to phenol-soluble modulin